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1. Differential Diagnosis

Ok guys, we have not really spent much time on differential diagnosis.
Can someone have a go at discussing the process of differential diagnosis if a patient presented with a condition that seemed a little out of the ordinary. What steps would you follow and why?

2. Pathogenesis

What is collagenase and where does it come from and what role does it play?

What is LPS, where does it originated from and what are its effects?